Pain Aid External Care

Mechanism of action of active ingredient: 

• Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are two essential and active components of medical cannabis (THC). THC, one of the active components in cannabis, activates CB1 and CB2 receptors, respectively .
• The metabolic mechanisms that create 2-arachidonoyl-sn-glycerol (2-AG), anandamide, and endocannabinoids in wounded tissues are known to reduce sensitization and inflammation by activating cannabinoid (CB) receptors .

● CBD and THC both help to relieve pain at the location of an injury. THC’s anti-inflammatory activities are primarily mediated via CB2 receptor activation on immune cells, which dampens the body’s pain-inducing reaction to damage. CBD, on the other hand, decreases inflammation by inhibiting inflammatory mediators and changing macrophage repair cells from pro-inflammatory to anti-inflammatory activation.